Maria Grazia Roncarolo on fast-tracking stem cell and gene therapy to the clinic

Leading stem-cell professional and also Stanford professor of pediatrics Maria Grazia Roncarolo, MD, will certainly be leading a session on stem cell and also gene treatment at Stanford’s inaugural Childx seminar this springtime. The session will concentrate on building as well as setting up strategies in genetics therapy, stem cells, and regenerative medicine to cure loads of childhood conditions....

Scientists discover how to change human leukemia cells into harmless immune cells

Majeti and his colleagues have some reason to hope that when the cancer cells become macrophages they will not only be neutralized, but may actually assist in fighting the cancer. Like a bloodhound owner who gives the dog a sniff of an object that was associated with the person or animal he wants to track, macrophage cells present recognizable bits of abnormal cells to other immune cells so that they...

Weissman obtains Brupbacher Reward, McEwen Award

Irving Weissman, MD, was granted the Charles Rodolphe Brupbacher Reward for Cancer cells Research study on Jan. 29 throughout an international seminar labelled “Developments in Cancer Research study as well as Therapy” in Zurich. Along with the Brupbacher Prize, it was just recently revealed that Weissman will certainly receive the McEwen Honor for Innovation, supported by the McEwen Centre...

Immune cells put their very own “eat me” tag on cancer cells

Stanford analysts previously found that kinds of cancer cells protect themselves from set cell elimination by displaying a “do not-eat-me” signal called CD47 to neutralize the “eat-me” signal presented by CRT on cancer cells. Professional scientists in the Stanford Cancer Institute are now carrying out a professional test of a treatment to view if blocking cancer’s CD47...

Researchers isolate stem cell that gives rise to bones, cartilage in mice

In addition to learning how to create bone, cartilage and stromal cells out of skeletal stem cells, the researchers found out how to create skeletal stem cells themselves out of fat or muscle cells. The ability to reprogram mature fat cells directly into skeletal stem cells through the application of specific signals “was really interesting and quite unexpected,” Longaker said. This work was supported...

Pluripotent cells produced by nuclear transfer could motivate immune reaction, researchers discover

Details about Stanford’s Division of Cardiothoracic Surgery, which likewise sustained the work, is offered at http://ctsurgery.stanford.edu. The other Stanford co-author of the paper is Robert Robbins, MD, former teacher of cardiothoracic surgical treatment. Additional co-authors are from the College Heart Center in Hamburg, the Cardiovascular Proving ground Hamburg, the German Center for Cardiovascular...

New molecular imaging technology could improve bladder-cancer detection, researchers say

Other Stanford co-authors are instructors Jens-Peter Volkmer, MD, and Debashis Sahoo, PhD; research associate Kathleen Mach, PhD; postdoctoral scholar Lei Kang, PhD; urology residents Timothy Chang, MD, and Jen-Jane Liu, MD; research assistant Thomas Metzner; professor of pathology Matt de van de Rijn, MD, PhD; and professor and chair of radiology Sanjiv Gambhir, MD, PhD. After 30 minutes, they rinsed...

Wernig wins stem cell prize, Giocomo named neuroscience investigator

“I wish to congratulate Dr. Giocomo and Dr. Wernig on these prestigious awards,” said Lloyd Minor, dean of the School of Medicine. “Stanford is a leader in stem cell research, and I am most grateful to the New York Stem Cell Foundation for this latest support and recognition of our outstanding faculty and their achievements in neuroscience and translational stem cell research.” Giocomo, PhD,...

Drug may prevent development of invasive bladder cancer, researchers say

Provocative finding The researchers gave laboratory mice BBN in their drinking water for four months — long enough to cause carcinomas in situ, but not invasive bladder cancers. They then split the mice into two groups, each of which continued to receive BBN for an additional month. One group also received a low dose of FK506 during that final month, while the other group received a placebo. They...

Five scientists nab awards for high-risk, high-return research

They are among the 85 recipients of the 2014 Pioneer, New Innovator, Transformative Research and Early Independence awards from the NIH. The awards are designed to encourage scientists to pursue creative research projects with the potential of leading to big improvements in health care. Wu’s lab is working on methods of creating synthetic blood vessels, heart valves and ventricular assist devices...